(*Corresponding authors, #Authors with equal contributions)
77. “Endoplasmic reticulum stress induces liquid-liquid phase separation of GRP78 and modulates protein aggregation dynamics”, submitted.
76. “Dexter energy transfer photocatalysis enables covalent labeling and profiling of amyloid plagues in alzheimer's disease tissue”, submitted.
75. “Proteotyping amyloidosis diseases by small molecule guided photocatalytic proteomics profiling”, submitted.
74. “Small molecules influence physical microenvironment of biomolecular condensates”, in review.
73. “Exploring endoplasmic reticulum dysfunction on protein phase separation using viscosity sensitive fluorescent lifetime probe”, in review.
72. “Investigating the interplay between iron-mediated protein aggregation and mitochondrial damage using polarity-sensitive fluorescent lifetime probes”, in review.
71. “The endoplasmic reticulum displays high polarity and prevents protein aggregation”, in review.
70. “Lysosomal RNA degradation and its unexpected link to purine synthesis and purinosomes”, in review.
69. “Hydrogen bonding-stabilized polymeric coacervate core micelle for enhanced hydrophobic drug delivery”, in review.
68. “Intracellular water potential sensing and response via biomolecular condensation”, in revision.
67. “Navigating condensate microenvironment to enhance small molecule drug targeting”, in revision.
66. “LipoID: a photochemical proteomic approach to in situ profile lipid droplets interactions and identify inter-organelle regulators”, in revision.
65. “Time-resolved fluorescent proteins towards fluorescence microscopy in the temporal and spectral domains”, in revision.
64. “Chemical control of fluorescence lifetime of molecular rotors provides insights into subcellular viscosities during ferroptosis”, accepted.
63. “Phosphorylation-dependent charge blocks regulate the relaxation of nuclear speckle networks”, accepted.
62. “1000-fold ultra-photosensitized fluorescent protein mimics towards photocatalytic proximity labeling and proteomic profiling functions”, accepted.
61. Zhou, L.; Zhu, L.; Wang, C.; Xu, T.; Wang, J.; Zhang, B.;* Zhang, X.;* Wang, H.* “Multiphasic condensates formed with mono-component of tetrapeptides via phase separation”, Nat. Commun. 2025, 16: 2706.
60. Wan, J.; Huang, C.; Chen, Z.; Wan, J.; Ding, W.; Liu, D.; Feng, L.; Meng, Y.; Li, M.; Ju, M.; Zhang, X.*; Shen, B.;* Huang, H.* “Smart fluorogenic tools: From designing principles to visualization of multistep protein aggregation”, Coord. Chem. Rev. 2025, 535: 216625.
59. Hsiung, C.-H.; Zhang, X.* “Mimicking fluorophores from nature to generate artificial fluorescent proteins and biosensors”, Nat. Chem. 2024, 16: 1934-1935.
58. Hurtle, B.; Donnelly, C. J.; Zhang, X.; Thathiah, A.* “Live-cell visualization of tau aggregation in human neurons”, Commun. Biol. 2024, 7: 1143.
57. He, X.; Li, J.; He, W.; Zhai, J.; Wei, Y.; Zhang, X.;* Shen, B.;* Huang, H.* “Exploring the interplay between zinc-induced protein dyshomeostasis and mitochondrial dysfunction using viscosity-sensitive sensor”, Smart Mol. 2024, e20240047.
56. Wei, Y.; Gao, X.; Fang, J.; Xiao, Y.; Liu, J.; Liu, Y.;* Zhang, X.;* Shen, B.* “Tailoring the pKa of fluorescence lifetime imaging probes to visualize aggrephagy and resolve its microenvironmental viscosity”, Anal. Chem. 2024, 96, 35: 14160–14167.
55. Guo, Y.; Zhang, X.* “Unveiling intracellular phase separation: advances in optical imaging of biomolecular condensates”, Trends Biochem. Sci. 2024, 49, 10: 901-915.
54. Zhu, L.; Pan, Y.; Hua, Z.; Liu, Y.; Zhang, X.* “Ionic effect on the microenvironment of biomolecular condensates”, J. Am. Chem. Soc. 2024, 146, 20: 14307–14317.
53. Ma, J.; # Luo, F.; # Hsiung, C.-H.; Dai, J.; Tan, Z.; Ye, S.; Ding, L.;* Shen, B.;* Zhang, X.* “Chemical control of fluorescence lifetime towards multiplexing imaging”, Angew. Chem. Int. Ed. 2024, 63, 25: e202403029.
52. Huang, Y.; Chang, M.; Gao, X.; Fang, J.; Ding, W.; Liu, J.; Shen, B.;* Zhang, X.* “NRhFluors: Quantitative revealing the interaction between protein homeostasis and mitochondria dysfunction via fluo-rescence lifetime imaging”, ACS Cent. Sci. 2024, 10, 4: 842-851.
51. Feng, H.; Zhao, Q.; Zhao, N.; Liang, Z.; Huang, Y.; Zhang, X.; Zhang, L.;* Liu, Y.* “A cell-permeable photosensitizer for selective proximity labeling and crosslinking of aggregated proteome”, Adv. Sci. 2024, 11, 18: 2306950.
50. Ma, J.;# Sun, R.;# Xia, K.;# Xia, Q.;# Liu, Y.;* Zhang, X.* “Design and application of fluorescent probes to detect cellular physical microenvironments”, Chem. Rev. 2024, 124, 4: 1738-1861.
49. Huang, Y.; Chen, J.; Hsiung, C.-H.; Bai, Y.; Tan, Z.; Ye, S.; Zhang, X.* “Detecting protein-protein interaction during liquid-liquid phase separation using fluorogenic protein sensors”, Mol. Biol. Cell 2024, 35, 3: ar41.
48. Hoelzel, C.;# Bai, Y.;# Wang, M.; Liu, Y.;* Zhang, X.;* “High-fidelity assay based on turn-off fluorescence to detect the perturbations of cellular proteostasis”, ACS Bio. & Med. Chem. Au. 2024, 4, 2: 111–118.
47. Zhang, X.;* Booker, S.* “Seeing is believing: advances in biological imaging”, ACS Bio. & Med. Chem. Au, 2024, 4: 1-3.
46. Wang, J.; Ma, X.; Hu, Y.; Feng, G.; Guo, C.; Zhang, X.; Ma, H.* “Regulation of micro- and small-exon retention and other splicing processes by GRP20 for flower development”, Nat. Plants 2024, 10: 66-85.
45. Ye, S.; Latham, A. P.; Tang, Y.; Hsiung, C.-H.; Chen, J.; Luo, F.; Liu, Y.; Zhang, B.; Zhang, X.* “Micropolarity governs the structural organization of biomolecular condensates”, Nat. Chem. Biol. 2024, 20: 443–451.
44. Latham, A. P.; Zhu, L.; Sharon, D. A.; Ye, S.; Willard, A. P.; Zhang, X.;* Zhang, B.* “Microphase separation produces interfacial environment within diblock biomolecular condensates”, eLife 2024, https://doi.org/10.7554/eLife.90750.3.
43. Dai, J.; Zhang, X.* “Chemical regulation of fluorescence lifetime”, Chem. Biomed. Imaging 2023, 1, 9: 796–816.
42. Bai, Y.;# Zhang, S.;# Dong, H.;# Liu, Y.; Liu, C.;* Zhang, X.* “Advanced techniques for detecting protein misfolding and aggregation in cellular environments”, Chem. Rev. 2023, 123, 21: 12254-12311.
41. Cheng, X.; Pu, Y.; Ye, S.; Xiao, X.; Zhang, X.; Chen, H.* “Measuring solvent exchange in silica nanoparticles with rotor-based fluorophore”, Adv. Mater. 2023, 2305779.
40. Zhang, X.* and Tang, B.* et al., “Aggregation-Induced Emission (AIE), Life and Health”, ACS Nano 2023, 17, 15: 14347–14405.
39. Liu, C.;* Zhang, X.* “Navigating the terrain of protein aggregation and phase separation - A chemical biology perspective”, Curr. Opin. Chem. Biol. 2023, 77: 102386.
38. Ma, Q.; Wang, M.; Huang, Y.; Nie, Y.; Zhang, X.; Yang, D. D.; Wang, Z.; Ding, S.; Qian, N.; Liu, Y.;* Pan, X.* “Identification of a novel transthyretin mutation D39Y in a cardiac amyloidosis patient and its biochemical characterizations”, Front. Cardiovasc. Med. 2023, 10: 1091183.
37. Jung, K. H.; Sun, J.; Hsiung, C.-H.; Lian, X. L.; Liu, Y.; Zhang, X.* “Nuclear bodies protect phase separated proteins from degradation in stressed proteome”, eLife 2023, https://doi.org/10.7554/eLife.88237.1.
36. Shen, B.; Liu, L.; Huang, Y.; Wu, J.; Feng, H.; Liu, Y.;* Huang, H.;* Zhang, X.* “Installing hydrogen bonds as a general strategyto control viscosity sensitivity of molecular rotor fluorophores”, Aggregate 2024, 5, 1: e421.
35. Shen, D.; Zhao, Q.; Wang, M.; Zhong, B.; Jin, W.; Huang, Y.; Jin, H.; Jing, B.; Wan, W.; Zhang, X.; Zhang, L.;* Liu, Y.* “Developing an affinity-based chemical proteomics method to in-situ capture amorphous aggregated proteome and profile its heterogeneity in stressed cells”, Anal. Chem. 2023, 95, 15: 6358–6366.
34. Zhang, Z.; Zhu, L.; Feng, J.; Zhang, H.;* Zhang, X.;* Sun, J.;* Tang, B.* “In situ monitoring of protein aggregation via clusteroluminescence”, Mat. Chem. Front. 2023, 7: 713-719.
33. Bai, Y.; Wan, W.; Huang, Y.; Wu, J.; Liu, L.; Jing, B.; Chen, J.; Zhang, X.;* Liu, Y.* “Tailoring the positive and negative solvatochromism for chalcone analogues to detect heterozygous protein co-aggregation”, Chem. Comm. 2023, 59: 4016–4019.
32. Feng, H.; Zhao, Q.; Zhang, B.; Hu, H.; Liu, M.; Wu, K.; Li, X.; Zhang, X.;* Zhang, L.;* Liu, Y.* “Enabling photo-crosslinking and photo-sensitizing properties for synthetic fluorescent protein chromophores”, Angew. Chem. Int. Ed. 2023, 62, 2: e202215215.
31. Shen, B.; Jung, K. H.; Ye, S.; Hoelzel, C. A.; Wolstenholme, C. H.; Huang, H.;* Liu, Y.;* Zhang, X.* “A dual-functional BODIPY-based molecular rotor probe reveals different viscosity of protein aggregates in live cells”, Aggregate 2023, 4, 3: e301.
30. Liu, L.; Huang, Y.; Zhou, Y.; Zhao, Y.; Qia, J.; Zhang, X.;* Shen, B.* “Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application”, Trends in Anal. Chem. 2022, 157: 116764.
29. Wang, L.; Hsiung, C.-H.; Liu, X.; Wang, S.; Loredo, A.; Zhang, X.;* Xiao, H.* “Xanthone-based solvatochromic fluorophores for quantifying micropolarity of protein aggregates”, Chem. Sci. 2022,13: 12540-12549.
28. Melo, E. P.; Konno, T.; Farace, I.; Awadelkareem, M. A.; Skov, L. R.; Teodoro, F.; Sancho, T. P.; Paton, A. W.; Paton, J. C.; Fares, M.; Paulo, P. M. R.; Zhang, X.; Avezov, E.* “Stress-induced protein disaggregation in the Endoplasmic Reticulum catalysed by BiP”, Nat. Commun. 2022, 13: 2501.
27. Ye, S.; Tang, Y.; Zhang, X.* “Principles, modulation and applications of fluorescent protein chromophores”, Chem. Phys. Rev. 2022, 3, 1: 011308.
26. Ye, S.; Hsiung, C.-H.; Tang, Y.; Zhang, X.* “Visualize the multi-step process of protein aggregation in live cells”, Acc. Chem. Res. 2022, 55, 3: 381–390.
25. Dion, W.; Ballance, H.; Lee, J.; Pan, Y.; Irfan, S.; Edwards, C.; Sun, M.; Zhang, J.; Zhang, X.; Liu, S.; Zhu, B.* “Four-dimensional nuclear speckle phase separation dynamics regulate proteostasis", Sci. Adv. 2022, 8: eabl4150.
24. Jiang, Y.; Chen, C.; Randolph, L. N.; Ye, S.; Zhang, X.; Bao, X.;* Lian, X.* “Generation of pancreatic progenitors from human pluripotent stem cells by small molecules”, Stem Cell Rep. 2021, 16, 9: 2395-2409.
23. Tang, S.; Wang, W.; Zhang, X.* “Direct visualization and profiling of protein misfolding and aggregation in live cells”, Curr. Opin. Chem. Biol. 2021, 64: 116-123.
22. Carter, G. C.; Hsiung, C.; Simpson, L. W.; Yang, H.; Zhang, X.* “N-terminal domain of TDP43 enhances liquid-liquid phase separation of globular proteins”, J. Mol. Biol. 2021, 433(10): 166948.
21. Tang, S.; Ye, S.; Zhang, X.* “When aggregation-induced emission meets protein aggregates”, Nat. Sci. Rev. 2021, 8, 6: nwab013.
20. Ye, S.; Zhang, H.; Fei, J.; Wolstenholme, C.; Zhang, X.* “A general strategy to control viscosity sensitivity of molecular rotor-based fluorophores”, Angew. Chem. Int. Ed. 2021, 60, 3: 1339-1346.
19. Wolstenholme, C. H.; Hu, H.; Ye, S.; Funk, B. E.; Jain, D.; Hsiung, C.-H.; Ning, G.; Liu, Y.;* Li, X.; * Zhang, X.* “AggFluor: Fluorogenic toolbox enables direct visualization of the multi-step protein aggregation process in live cells”, J. Am. Chem. Soc. 2020, 142, 41: 17515–17523. (highlighted by JACS Spotlights, Protein Aggregation: It’s a Process).
18. Hoelzel, C. A.; Zhang, X.* “Visualizing and manipulating biological processes using HaloTag and SNAP-Tag technologies”, ChemBioChem 2020, 21, 14: 1935-1946.
17. Jung, K. H.; Zhang, X.* “Fluorogenic detection of protein aggregates in live cells using the AggTag method”, Methods Enzymol. 2020, 639: 1-22.
16. Hoelzel, C. A.; Hu, H.; Wolstenholme, C. H.; Karim, B. A.; Munson, K. T.; Jung, K. H.; Zhang, H.; Liu, Y.; Yennawar, H. P.; Asbury, J. B.; Li, X.;* Zhang, X.* “A general strategy to enhance donor-acceptor molecules using solvent-excluding substituents”, Angew. Chem. Int. Ed. 2020, 59, 12: 4785-4792.
15. Kim, S. H.; Liu, Y.; Hoelzel, C.; Zhang, X.;* Lee, T.H.* “Super-resolution optical lithography with DNA”, ACS Nano Letter 2019, 19, 9: 6035-6042.
14. Jung, K. H.; Kim, S. F.; Liu, Y.; Zhang, X.* “A fluorogenic AggTag method based on Halo- and SNAP-tag to simultaneously detect the aggregation of two proteins in live cells”, ChemBioChem 2019, 20, 8: 1078-1087.
13. Jung, K. H.; Fares, M.; Grainger, L. S.; Wolstenholme, C. H.; Hou, A.; Liu, Y.; Zhang, X.* “A SNAP-tag fluorogenic probe mimicking the chromophore of the red fluorescent protein Kaede”, Org. Biomol. Chem. 2019, 17, 7: 1906-1915.
12. Liu, Y.; Fares, M.; Zhang, X.* “Monitoring proteome stress in live cells using HaloTag-based fluorogenic sensor”, Methods Mol. Biol. 2019, 1873: 171-182.
11. Fares, M.; Zhang, X.* Quantification of cellular proteostasis in live cells by fluorogenic assay using the AgHalo sensor”, Curr. Protoc. Chem. Biol. 2018, 11, 1: e58.
10. Hu, H.; Wolstenholme, C. H.; Zhang, X.;* Li, X. S.* “Inverted solvatochromic stokes shift in GFP-like chromophores with extended conjugation”, Chin. J. Chem. Phys. 2018, 31, 4: 599-607.
9. Liu, Y.; Miao, K.; Li, Y.; Fares, M.; Chen, S.; Zhang, X.* “A HaloTag-based multi-color fluorogenic sensor visualizes and quantifies proteome stress in live cells using solvatochromic and molecular rotor-based fluorophores”, Biochemistry 2018, 57, 30: 4663-4674.
8. Leach, B. I.; Zhang, X.; Kelly, J. W.; Dyson, H. J.; Wright, P. E.* “NMR measurements reveal the structural basis of transthyretin destabilization by pathogenic mutations”, Biochemistry 2018, 57: 4421-4430.
7. Liu, Y.; Wolstenholme, C. H.; Carter, G.; Liu, H.; Hu, H.; Grainger, L. S.; Miao, K.; Fares, M.; Hoelzel, C. A.; Yennawar, H.; Ning, G.; Du, M.; Bai, L.; Li, X.; Zhang, X.* “Modulation of fluorescent protein chromophores to detect protein aggregation with turn-on fluorescence”, J. Am. Chem. Soc. 2018, 140, 24: 7381-7384.
6. Pedley, A.; Karras, G.; Zhang, X.; Lindquist, S.; Benkovic, S.* “Role of HSP90 in the regulation of de novo purine biosynthesis”, Biochemistry 2018, 57, 23: 3217-3221.
5. Li, X.; Wang, T.; Duan, P.; Baldini, M.; Huang, H.; Chen, B.; Juhl, S.; Koeplinger, D.; Crespi, V.; Schmidt-Rohr, K.; Hoffmann, R.; Alem, N.; Guthrie, M.; Zhang, X.; Badding, J.* “Carbon nitride nanothread crystals derived from pyridine”, J. Am. Chem. Soc. 2018, 140, 15: 4969-4972.
4. Liu, Y.; Zhang, X.* “Heat shock protein reports on proteome stress”, Biotechnology J. 2018, 13, 4: 1800039.
3. Fares, M.; Li, Y.; Liu, Y.; Miao, K.; Gao, Z.; Zhai, Y.; Zhang, X.* “A molecular rotor-based Halo-tag ligand enables a fluorogenic proteome stress sensor to detect protein misfolding in mildly stressed proteome”, Bioconjugate Chem. 2018, 29, 1: 215-224.2.
2. Liu, Y.; Fares, M.; Dunham, N. P.; Gao, Z.; Miao, K.; Jiang, X.; Bollinger, S. S.; Boal, A. K.; Zhang, X.* “AgHalo: A facile fluorogenic sensor to detect drug induced proteome stress”, Angew. Chem. Int. Ed. 2017, 56, 30: 8672-8676.
1. Liu, Y.; Miao, K.; Dunham, N. P.; Liu, H.; Fares, M.; Boal, A. B.; Li, X.; Zhang, X.* “The cation-π interaction enables a Halo-Tag fluorogenic probe for fast no-wash live cell imaging and gel-free protein quantification”, Biochemistry 2017, 56, 11: 1585-1595, (ACS Editor’s Choice). Featured by Viewpoint in Biochemistry.
From Scripps and Caltech:
36. Liu, Y.;# Zhang, X.;# Chen, W. T.; Tan, Y. L.; Kelly, J. W.* “Fluorescence turn-on folding sensor to monitor proteome stress in live cells”, J. Am. Chem. Soc. 2015, 137, 35: 11303-11311, (co-first authors).
35. Cho, Y. H.; Zhang, X.; Liu, Y.; Fayer, K.; Powers, D. L.; Kelly, J. W.; Gierasch, L.;* Powers, E. T. * “Individual and collective contributions of chaperonin and degradation to protein homeostasis in E. coli”, Cell Reports, 2015, 11, 2: 321-333.
34. Liu, Y.;# Tan, Y. L.;# Zhang, X.;# Bhabha, G.; Ekiert, D.; Genereux, J. C.; Cho, Y. H.; Kipnis, Y.; Bjelic, S.; Baker, D.; Kelly, J. W.* “Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts”, Proc. Nat.l Acad. Sci. (USA) 2014, 111, 12: 4449-54.
33. Zhang, X.; Liu, Y.; Genereux, J. C.; Nolan, C.; Singh, M.; Kelly, J. W.* “Heat-shock response transcriptional program enables high-yield and high-quality recombinant protein production in Escherichia coli”, ACS Chem. Biol. 2014, 9: 1945−1949. (ACS Editor’s Choice)
32. Liu, Y.;# Zhang, X.;# Tan, Y. L.; Bhabha, G.; Ekiert, D.; Kipnis, Y.; Bjelic, S.; Baker, D.; Kelly, J. W.* “De novo designed enzymes as small molecule-regulated fluorescence imaging tags and fluorescent reporters”, J. Am. Chem. Soc. 2014, 136, 38: 13102-13105 (co-first authors).
31. Zhang, X.; Kelly, J. W.* “Chaperonins resculpt folding free energy landscapes to avoid kinetic traps and accelerate protein folding” J. Mol. Biol. 2014, 426, 15: 2736-2738.
30. Zhang, X.; Shan, S.* “Fidelity of co-translational protein targeting by the signal recognition particle”, Ann. Rev. Biophysics 2014, 43: 381-408.
29. Akopian, D.;# Shen, K.;# Zhang, X.;# Shan, S.;* “Signal recognition particle: An essential targeting machine”, Ann. Rev. Biochemistry 2013, 82: 693-722 (co-first authors listed alphabetically).
28. Li, X.;* Zhang, X.; Ladiwala, A. R.; Du, D.; Yadav, J.; Tessier, P.; Wright, P.; Kelly, J. W.; Buxbaum, J.* “Mechanism of transthyretin inhibition of β-amyloid aggregation in vitro”, J. Neuroscience 2013, 33, 50: 19423-19433.
27. Von Loeffelholz, O.; Knoops, K.; Ariosa, A.; Zhang, X.; Karuppasamy, M.; Huard, K.; Schoehn, G.; Berger, I.; Shan, S.;* Schaffitzel, C.* “Structural basis of signal sequence surveillance and selection by the SRP-FtsY complex”, Nat. Struct. Mol. Biol. 2013, 20: 604-610.
26. Liu, X.;# Wei, W.;# Yuan, Q.; Zhang, X.; Li, N.; Du, Y.; Ma, G.; Yan, C.; Ma, D.* “Apoferritin–CeO2 nano-truffle that has excellent artificial redox enzyme activity”, Chem. Comm. 2012, 48: 3155-3157.
25. Zhang, X.; Lam, V. Q.; Mou, Y.; Kimura, T.; Chung, J.; Chandrasekar, S.; Winkler, J. R.; Mayo, S. L.; Shan, S.* “Direct visualization reveals dynamics of a transient intermediate during protein assembly”, Proc. Natl. Acad. Sci. (USA) 2011, 108, 16: 6450-55.
24. Shen, K.; Zhang, X.; Shan, S.* “Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during co-translational protein targeting”, RNA 2011, 17, 5: 892-902.
23. Yang, M. J.; Zhang, X.* “Molecular dynamics simulations reveal structural coordination of Ffh-FtsY heterodimer towards GTPase activation”, Proteins: Struc., Funct., Bioinf. 2011, 79, 6: 1774-1785.
22. Yang, M. J.; Pang, X. Q.; Zhang, X.; Han, K.* “Molecular dynamics simulation reveals preorganization of the Chloroplast FtsY towards complex formation induced by GTP-binding”, J. Struct. Biol. 2011, 173, 1: 57-66.
21. Zhang, X.; Rashid, R.; Wang, K.; Shan, S.* “Sequential checkpoints govern substrate selection during co-translational protein targeting”, Science 2010, 328, 5979: 757-60.
20. Yang, M. J.; Zhang, X.; Han, K.* “Molecular dynamics simulation of SRP GTPases: towards an understanding of complex formation from equilibrium fluctuations”, Proteins: Struc., Funct., Bioinf. 2010, 78, 10: 2222-2237.
19. Zhang, X.; Schaffitzel, C.; Ban, N.; Shan, S.* “Multiple conformational switches in a GTPase complex control co-translational protein targeting”, Proc. Natl. Acad. Sci. (USA) 2009, 106, 6: 1754-59.
18. Schmid, S. L.; Zhang, X.; Shan, S.* “Signal recognition particle (SRP) and SRP receptor: A new paradigm for multi-state regulatory GTPases”, Biochemistry 2009, 48, 29: 6696–6704.
17. Wu, E. L.; Wong, K.; Zhang, X.; Han, K.;* Gao, J.* “Determination of the structure form of the fourth ligand of zinc in acutolysin a using combined quantum mechanical and molecular mechanical simulation”, J. Phys. Chem. B 2009, 113, 8: 2477–2485.
16. Zhang, X.; Kung, S.; Shan, S.* “Demonstration of a multistep mechanism for assembly of the SRP•SRP receptor complex: Implications for the catalytic role of SRP RNA”, J. Mol. Biol. 2008, 381, 3: 581-593.
15. Zhang, X.; Han, K.* “High-order symplectic integration in quasi-classical trajectory simulation: Case study for O(1D)+H2”, Int. J. Quant. Chem. 2006, 106, 8: 1815-1819.
14. Chu, T.; Zhang, X.; Ju, L.; Yao, L.; Han, K.;* Wang, M.; Zhang, J. Z. H.* “First principles quantum dynamics study reveals subtle resonance in polyatomic reaction: The case of F+CH4 → HF+CH3”, Chem. Phys. Lett. 2006, 424, 4-6: 243-246.
13. Chen, X.; Zhang, X.; Han, K.;* Varandas, A. J. C.* “ab initio study of the H+ClONO2 reaction”, Chem. Phys. Lett. 2006, 421, 4-6: 453-59.
12. Ju, L.; Xie, T.; Zhang, X.; Han, K.* “A modified potential energy surface for the C2H+H2↔ C2H2+H reaction and a theoretical study on its rate constants”, Chem. Phys. Lett. 2005, 409, 4-6: 249-254.
11. Chu, T.; Zhang, X.; Han, K.* “A quantum wave-packet study of intersystem crossing effects in the O(3P, 1D)+H2 reaction”, J. Chem. Phys. 2005, 122, 21: 214301-214306.
10. Yang, G.; Yao, L.; Zhang, X.; Meng, Q.; Han, K.* “Theoretical study of the mechanism for spin-forbidden quenching process O(1D)+CO2 (1Sg+) → O(3P)+CO2 (1Sg+)”, Int. J. Quant. Chem. 2005, 105, 2: 154-159.
9. Yang, C.;* Zhang, X.; Han, K. “Theoretical study on analytical potential function and spectroscopic parameters for CaF molecule”, J. Mol. Struct-Theochem 2004, 678, 1-3: 183-188.
8. Yang, C.;* Zhang, X.; Han, K. “ab initio geometries, electronic structures of MgB2 molecule”, J. Mol. Struct-Theochem 2004, 677, 1-3: 11-14.
7. Yang, C.;* Zhang, X.; Han, K. “Analytical potential energy function and spectroscopic parameters for the ground and excited states of NaH”, J. Mol. Struct-Theochem 2004, 676, 1-3: 209-213.
6. Yang, G.;* Zhang, X.; Meng, Q.; Han, K. “Theoretical studies on the intermediate complex mechanism of the energy transfer reaction of O(1D)+CO2 (1Sg+) → O(3P)+CO2 (1Sg+)”, Chem. J. Chin. Univ. 2004, 25, 4: 689-692.
5. Yang, G.; Meng, Q.; Zhang, X.; Han, K.* “Theoretical study on the formation mechanism of Iso-CH2l-Cl”, Int. J. Quant. Chem. 2004, 97, 2: 719-724.
4. Zhang, X.; Yang, G.; Han, K.;* Wang, M.; Zhang, J. Z. H. “Quantum dynamics study of isotope effect for H + CH4 reaction using the SVRT model”, J. Chem. Phys. 2003, 118, 20: 9266-9271.
3. Yang, C.;* Huang, Y.; Zhang, X.; Han, K. “MRCI potential curve and analytical potential energy function of the ground state of H2”, J. Mol. Struct-Theochem 2003, 625, 1-3: 289-293.
2. Zhang, X.; Han, K.;* Zhang, J. Z. H. “SVRT calculation for bond-selective reaction H+HOD → H2+OD, HD+OH”, J. Chem. Phys. 2002, 116, 23: 10197-10200.
1. Zhang, X.; Xie, T.; Zhao, M.; Han, K.* “Quasiclassical trajectory simulation of the chemical reaction Ba+HF (n, J) → BaF (n‘, J‘)+H”, Chin. J. Chem. Phys. 2002, 15, 3: 169-174.